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For poorly differentiated NETs, a platinum-based regimen should be considered.
Therefore, on the basis of these studies, children failing NNRTI-based regimens should be switched early, although there may be less urgency in those failing boosted protease inhibitor based regimens.
Therefore, taxane-based regimens should be tested in a randomised trial and compared with a less intensive concurrent regimen.
Folic acid based regimens should not be used for the prevention of cardiovascular events in people with kidney disease.
In the absence of direct comparisons between currently used anthracycline-based regimens, the definition of standard regimen should be based on a demonstrated superiority over the CMF.
Our data supports that the CI maintenance-dosing regimen should be based on CVVH flow rate because a positive correlation was found between the intensity of CVVH and vancomycin clearance in patients who received CI.
The selection of an antimicrobial regimen should be based on local microbial and resistance patterns.
Reasonable dosage regimen should be based on PK/PD studies and determined by practical application of the test animals.
In relation to this assessment, the decision as to whether to continue or to modify the therapeutic regimen should be based (Fig. 2).
As the response to eradication therapy is significantly related to the prevalence of primary resistance in the population, the choice of a treatment regimen should be based on the knowledge of the underlying prevalence of resistant strains in the community, which needs to be monitored.
73 As the response to eradication therapy is related to the prevalence of primary resistance in the population, the choice of a treatment regimen should be based on a knowledge of the underlying prevalence of resistant strains in the community and on the patient's history (no treatment or previous treatments).
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