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Use of a single or multiple protease inhibitor based regimen was not associated with risk of hepatotoxicity in either naïve or experienced patient groups to a statistically significant extent.
Age and administration of tamoxifen were found to be significant predictive factors of CIA, whereas docetaxel and navelbine based regimens were not associated with higher rates of CIA than epirubicin-based regimen.
When enterococci were also considered, all betalactam based regimens required combination with vancomycin or linezolid for a SAR > 95%%, whereas TGC based regimens were not compromised.
Moreover, the selection of patients who may benefit from a bevacizumab-based regimen is not clear yet, this fact being a critical issue because of its high cost.
Regarding type of first-line treatment, in terms of treatment response our data showed that PI-based regimens were not superior to those based on efavirenz.
Protease inhibitor (PI) based regimens were reported by 16 studies.
In the adjuvant setting, the choice of treatment regimen is not modified based on the presence of such a predisposition.
The regimen is not being developed further, however, based on disappointing results obtained in four phase III studies of sunitinib in patients with ABC [ 26- 29].
However, this immunosuppressive drug regimen is not represented in current standard animal models of invasive fungal infections, which are typically based upon hydrocortisone alone (Sheppard et al., 2006).
When the regimen is not completed, particular TB strains can become drug-resistant.
The optimal insulin regimen is not clear.
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