It is, to our knowledge, the first report to present data on the effect of screening with flexible sigmoidoscopy from a large scale population based randomised controlled trial.
11 The NORwegian Colorectal CAncer Prevention (NORCCAP) trial 1 is a population based randomised controlled trial for the prevention of colorectal cancer, comparing once only flexible sigmoidoscopy with no screening (usual care).
Our analysis uniquely represents a detailed long term economic evaluation of a structured education programme based on results from a UK based randomised controlled trial that was carried out in accordance with a robust evaluation framework.
Drawing on the success and lessons from these studies, the Promise EBF community based randomised controlled trial (RCT) utilising CHWs trained in infant feeding peer counselling was initiated (Clinicaltrials.gov: NCT00397150).
This is the first population based randomised controlled trial of its kind in Indo-Asia to test the impact of such strategies in lowering blood pressure levels in the population.
From 1996 to 1998, 10,537 individuals, aged 20 59 years, registered with seven general practices in Southwest England were enrolled in a community based randomised controlled trial of eradication of Helicobacter pylori (H. pylori).
Three community-based randomised controlled trials, where misoprostol was administered at homebirths or at primary healthcare centres, have demonstrated safe and effective use of misoprostol for PPH prevention.
However, in the current era of evidence-based dentistry and care, systematic reviews and meta-analyses, based on randomised controlled trials, are considered top of the hierarchy concerning efficacy of preventive interventions and therapies.
20 23 The most recent reviews, based on randomised controlled trials (RCTs), have indicated that when compared with a control group (eg, waitlist control), CBT can be effective in the treatment of problem gambling, with growing evidence to support the use of MI interventions.
