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Two functionalized rhodamine based probes have been rational designed and synthesized.
Thus far, open-ended rectangular waveguide based probes have been used to inspect the structural integrity and homogeneity of these structures.
Nevertheless, alternatives for LNA based probes have been reported (Søe et al., 2011).
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The nanocluster based probe has been successfully applied to detect cancer cells with high precision.
A novel three-way junction DNAzyme based probe has been designed for the colorimetric sensing of target DNA.
In the present work, a unique pH sensitive non-cytotoxic gold nanocluster based probe has been synthesized to precisely detect sharp change in biological pH.
One area where such activity-based probes have been applied is the ubiquitin proteasome pathway, which is emerging as an important therapeutic target.
QD-based probes have been used for co-immunoprecipitation and Western blot analysis, allowing for simpler and faster image acquisition and quantification than traditional methods (Fig. 4) [105–108].
Reactivity-based probes have been developed to enable specific isolation of histone demethylases from nuclear lysates.
Similarly, a few other fluorescent-based probes have been developed to image histone acetylation in cells and small animals.
While a variety of virus-based probes have been reported in the literature, detailed studies about their optical properties have not been reported.
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