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Previously, it has been shown that the composition-based approaches are useful to develop machine learning based prediction of biological sequences [ 24].
Hybrid is a combined approach based prediction of all predicated SVM scores of MNC, DNC, TNC, TTNC and PNC approaches.
However, computer based prediction of the functional effect this mutation, using PolyPhen [ 24] and SIFT [ 25], revealed negative results (Table 1).
WGCNA based prediction of lncRNA functions associated lncRNAs to different modules with function-known genes, and classified them into different functional groups.
Finally, we evaluate the performance of gene fusion based prediction of protein-protein interaction and functional association, using these derived functional classes.
RNA-seq based prediction of operons and transcription start sites (TSS) within this genomic island (GI) was carried out using ReadXplorer (Hilker et al. 2014).
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Hence, context-based analysis reinforced our earlier sequence/structure-based prediction of phosphothreonine lyase catalytic function for BLES03.
The CASVM web server for support-vector-machines-based prediction of caspase cleavage sites [49] predicts 5 cleavage sites in OCT4 (Figure S8).
Since structural information is not available in the case of sequence-based prediction of stability changes, we employed predicted structural features.
This may be the result of dependence of sequence-based prediction of conformational flexibility and disorder, which may already be included in the sequence based features.
To accomplish this, Bartender performs track-based prediction of future signal strength at little energy cost.
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