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Table 1 shows that the AR and ER signal based pathways are the top two regulatory signaling pathways after metabolic and other enzymatic pathways that are listed.
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It is known that base excision repair pathways are the primary cellular response to alkylation damage [1], [28], [29], [30], [31], [32], though Y family DNA polymerases are also part of this response [1], [19], [20], [21].
The Base excision repair (BER) pathway is the main mechanism for removal of endogenously generated DNA base damage [ 1].
Based on a product in one pathway being the substrate of another pathway, the essential pathways were linked together and then integrated into their possible functions.
The main 8-oxoG repair pathway is the base excision repair (BER).
Given that BCL-2 is overexpressed in many tumors, most strategies to engage apoptosis pathways are based in the blockade of anti-apoptotic members of the BCL-2 family.
These pathways are based on the existing literature and variables available in the main dataset used in the analysis.
All three of these pathways are based on the idea that loved ones share social norms, the implicit cultural beliefs that make some things okay, others not.
Canonical pathways are based on the literature (journal article, KEGG pathways) and are used to overlay expression changes.
Numerous cellular signaling pathways are based on the sequential phosphorylation of an array of proteins [ 15, 33, 46].
Reaction pathways are proposed based on the experimental results.
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CEO of Professional Science Editing for Scientists @ prosciediting.com