Sentence examples for based only on sequence from inspiring English sources
Our goal was to use these 3D structures to obtain reliable multiple sequence alignments comprising more residues than the ones based only on sequence alignments.
The used threading algorithm is not based only on sequence similarity, but it also combines various scoring functions designed to match structurally related target/template pairs [24].
Majority of these miRNAs have been identified based only on sequence similarity to known vertebrate miRNA orthologs and have never been confirmed experimentally [3], [11].
The regions with significantly conserved strong / weak folding signals cannot be explained based only on sequence conservation.
The reason of enzyme function prediction based only on sequence information is due to the easily available sequence data.
Based only on sequence analysis, Miller and Kumar (2001) observed that disease-associated mutations in seven genes were particularly concentrated in conserved amino acid positions.
These four species are found at important topological positions with respect to the origin of GnRH receptor clades, but the presence or absence of homologs based only on sequences used for phylogenetic analyses constituted a potentially biased sample.
Classifying proteins into functionally distinct families based only on primary sequence information remains a difficult task.
Our method is based only on primary sequence information, and it can be used for the research of drug target and drug design in identifying PDZ domain-ligand interactions.
Consequently, a previous work based only on DNA sequence had to use a large input parameter set and multilayered feed-forward ANN architecture trained using the error-back-propagation algorithm to raise an overall accuracy up to 97% [Kalate, et al. 2003. Comput. Biol. Chem. 27, 555 564].
Fourth, based only on single sequence fragments from the virome, the complete DNA-A or DNA-B of novel viruses, as well as numerous satellite genomes were obtained by PCR.
