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Consequently, a previous work based only on DNA sequence had to use a large input parameter set and multilayered feed-forward ANN architecture trained using the error-back-propagation algorithm to raise an overall accuracy up to 97% [Kalate, et al. 2003. Comput. Biol. Chem. 27, 555 564].
However, functional DREs are very difficult to predict based only on DNA sequence information.
There was no obvious correlation with OS based only on DNA concentration in plasma.
Although the HSL model provides a useful tool to predict potential core TRRs based only on DNA sequence information, it may still yield high FP rates, especially for complex organisms, such as Homo sapiens.
We identified four categories of companies providing: 1) services based only on self-reported data, such as personal or family history; 2) services based only on DNA provided by the client; 3) services using both; and 4) services using both that also have a research component.
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Two of the 15 cases with missense mutations showed alterations based only on cDNA, and not DNA sequencing.
For the analysis based only on microsatellite DNA, the logistic regression value for the trifurcation scenario is much higher (0.5833, 95% confidence interval (CI =0.5605 0.6061) compared with the next highest scenario, scenario 7 where Italy splits from Spain (0.129, 95% CI=0.1138 0.1443).
So the researchers used statistical methods similar to those employed by biologists to trace species lineages back through the branching tree of evolution based only on modern DNA sequences.
Firstly, it provides a method for the unambiguous identification of kinetoplast and nuclear DNA in micrographs based only on the sequence bias of the DNA present in the organelle.
Motivation: Recognition models for protein-DNA interactions, which allow the prediction of specificity for a DNA-binding domain based only on its sequence or the alteration of specificity through rational design, have long been a goal of computational biology.
Comparative mutation rate in this study was based only on the genomic sequences of the cloned DNA-derived DEN4 from passages 1 through 3, the latter representing microcarrier culture viruses.
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