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Xia [10] integrated the two conventional hypotheses mentioned above and developed a new general hypothesis based on wobble cost as WCH.
We will refer to this new general hypothesis based on wobble cost as WCH (for wobble cost hypothesis).
In summary, our general hypothesis based on wobble costs allows the integration of the two conventional hypotheses (i.e., CAAH and WVH) on codon-anticodon wobble pairing.
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The Berkeley and Stanford teams are involved in two major exoplanet searches: a highly successful search for exoplanets based on the wobble they produce in a star's motion or the dimming they create when they transit in front of a star; and a newly launched survey by the Gemini Planet Imager to directly take pictures of planets by capturing the heat they give off.
Putative splicing regulatory sequences were reported based on evolutionary conserved wobble positions between human and mouse orthologous exons, along with overabundance of sequence motifs compared to their random expectation [ 11].
Transit detection can pick up much smaller planets than previous methods based on gravity-induced wobbles in the stellar parent.
By observing those stars closely, scientists can spot them wobbling as the planets circle — and based on how much they wobble, scientists can estimate the density of the planet, which gives them a sense of what the planet's made of.
From Boston and performing for free, the troupe will mix modern dance, gymnastics, circus and martial arts, vocal work and theater in "The Temperamental Wobble," based on the drawings of Edward Gorey, and "Flip/Switch," a mix of repertory.
Here we develop a general hypothesis of codon-anticodon adaptation based on an analysis of wobble costs, and derive its predictions that can be tested by genomic data.
For instance, codon preferences in A. thaliana correspond well with expectations based on tRNA abundances and wobble rules, and highly expressed genes show a higher frequency of preferred codons, as expected under models of translational accuracy or efficiency (Wright et al. 2004).
We here integrate these two traditional hypotheses on tRNA anticodons into a unified model based on an analysis of the wobble costs associated with different wobble base pairs.
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