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For example, AT1G61620, AT1G66040, AT1G66050 and AT5G39550 proteins are all annotated as FYVE proteins but do not actually possess FYVE domains based on various sequence analysis methods.
The computation results include possible catalytic residues ranked by their scores, which are calculated based on various sequence and structure features.
We have investigated the organism specific recognition of protein-RNA complexes based on various sequence and structure based features such as binding propensity, preference of residues at conserved positions, binding segments, binding motifs, neighboring residues and interacting amino acid-nucleotide pairs.
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PSORT (37) predicts localization based on various sequence-derived features such as sorting signals, binding domains and amino acid composition.
We used a computational analysis to identify genes lost as pseudogenes based on various detrimental sequence mutations such as in-frame stop codons and frameshifts causing or resulting from loss of function.
Based on various BLAST sequence comparisons to several databases (see Methods and Additional file 1), these unigenes were functionally characterized into the following groups: Putative secreted (S), putative housekeeping (H), transposable element-derived (TE), and of unknown class (U), because they could not be classified (some of which may derive from untranslated regions of mRNAs) (Table 1).
Recently, Sylvioidea has gone through a profound rearrangement based on various sets of molecular sequence data [ 14- 18].
Indeed, the aforementioned sequence-based algorithms make predictions based on various important features of miRNA and mRNA nucleotide sequence interaction.
SVM-Prot is a general proteome-wide function-prediction software based on various features of primary sequences.
These scores are computed based on various different approaches, such as sequence homology, evolutionary conservation, protein structure or statistical prediction based on known mutations.
The main advantage of our feature extraction methods over existing techniques is that features are extracted from the full length protein sequence based on various coding schemes without referencing external databases.
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