Construct validity is based on validation strategies developed by psychologists, who for many years have struggled with determining whether questionnaires assessing intelligence and attitudes really measure what is intended.
Ultimate evaluation of the method should be based on validation.
We hypothesized, based on validations done for other laboratory-based conditions by our research group, that our best performing algorithm would demonstrate limited sensitivity but excellent specificity for the identification of CKD [ 3- 6].
Based on previous validation by an experimenter, freezing was defined as subthreshold activity (set at 19 activity units) for >1 second.
As it can be assumed, based on the validation by Western blot, that both antibodies are specific for MT1-MMP, it is striking that ab7 did label RGC axons while ab8 did not.
Our experiments provide methodology to achieve accurate Ki67-LI estimation by DIA, based on proper validation, calibration, and measurement error correction procedures, guided by quantified bias from reference values obtained by stereology grid count.
The theoretical validation was based on cross-validation.
Based on calibration and validation by field experiment data, HYDRUS model was used to evaluate the impacts of design parameters of filter hydraulic conductivity, filter width and height, drain spacing and depth on improved subsurface drainage discharge with constant ponding depth.
The choice of the appropriate covariate combination is made by introducing a method based on cross validation (CV).
We first estimate the induced relative risk function with a kernel smoother based on the validation sample, and then improve the estimation by utilizing the information on the incomplete observations from the non-validation subsample.
Prediction accuracies based on independent validation are generally lower than those based on cross-validation.
