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Tumor-molecular directed therapy based on validated targets (EGFR, ALK) is in the clinics, rapidly, with the developments of multi-targets or multi-drug assays there will be a need for tumor-molecular-profile directed therapy.
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The database miRTarBase 4.5 (Hsu et al. 2014) was used to identify potential targets based on validated miRNA-target interactions in human, mouse, or rat.
Our dataset was based on validated miRNA targets including the previously documented cases of transitivity (i.e. PPR and AGO1 genes [10], [13]).
Using a dataset based on validated Arabidopsis miRNA targets, the machine was internally tested based on accuracy, precision, sensitive and specificity.
Consequently, the identification of anti-DFS70 antibodies should be based on validated procedures.
The psychological questionnaires were based on validated constructs (see section "Questionnaires").
Computational image analysis methods can be developed based on validated models.
Based on validated analytical models, long term performance of a single borehole GHE is determined.
All measurements in this study were based on validated scales.
These outline a ranked algorithm for T2DM treatment based on validated (first line) and less well-validated (second line) therapies.
Our definition of AS from administrative databases, as aforementioned, is reliable and based on validated algorithms.
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