Second, choosing the method for the primary analysis based on trial data has been shown to lead to unreliable results in several settings [ 1- 4].
Various selected studies in this review were strongly based on clinical trial settings.
Two meta-analyses, mainly based on trials in low and medium income settings, have shown that delayed cord clamping improves serum ferritin concentration at 3 6 months of age without affecting haemoglobin.
When clinical decisions in real-world settings are based on trials in which half of all participants received suboptimal care (BSC) in comparison with the BSC benchmark set by Temel et al, patients may not realise the net clinical benefit, including the survival advantage that studies suggest.
This standard was based on one trial for all exercises.
We stratified the trials based on these settings for the meta-analysis and calculated risk ratios (RR) for dichotomous outcomes, mean difference (MD) for continuous outcomes measure on the same scale, and standardized mean difference (SMD) for continuous outcomes measured using different scales.
Further, ten replications were conducted based on different settings of (D^T), (D{^G},), and (D^V) for StarPlus dataset, while twelve replications were performed for Haxby dataset such that each trial was used exactly once as test set.
