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Based on trial experience during the first nine months of recruitment, we expect that approximately 10% of patients will be ineligible due to cell phone criteria and another 10% will decline participation.
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While modern science has often confirmed the time-honored empirical knowledge, it has not and cannot entirely replace the kind of knowledge passed from generation to generation based on trial and error experiences over centuries and even millennia.
Based on trial data and our own experience we developed local protocols for the management of AAV with the aim of optimising the clinical care and outcomes of patients with AAV.
The design of neural network model is based on trial and error processes and requires past experience for successful implementation.
The design and development of rolls and processes are mainly based on trial-and-error and past experiences.
Traditionally the design process for bending and flanging tools is based on trial-and-error and on the skill of experienced die-makers.
The selection of an effective and specific antisense oligonucleotide is largely based on investigators' experience and trial-based experiments.
Based on the clinical trial experience of the last few years with antiangiogenic agents in HCC, certain "class" toxicity profiles have emerged.
The toolkit has been created for the purpose of the present trial, based on previous experience from the DEFENCE study, and consists of standardized protocols for all geriatric conditions that follow international guidelines and are all evidence based or based on current best practices [ 23].
In what follows, based on our experience conducting trials in low-income settings, we outline nine key factors that will need to be taken into account in any adequate approach to assent in research with children in these settings.
This method has great potential compared with the conventional ones relying on physical implementation based on human experience followed by trial-and-error correction.
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CEO of Professional Science Editing for Scientists @ prosciediting.com