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Technoeconomic analysis of a similar cellulase production system based on transgenic N. tabacum concludes that the plant-based system may offer a >30% reduction in unit production costs and an 85% reduction in the required capital investment compared with the current fungal-based fermentation system [ 49].
The assay is based on transgenic Arxula adeninivorans yeast cells as the bio-component.
In adult tissues, where cell dynamics is constrained by the condition of homeostasis, clonal tracing studies based on transgenic animal models have advanced our understanding of cell fate behaviour and its dysregulation in disease1,2.
Population modification strategies based on transgenic mosquitoes carrying genes that prevent parasite transmission play a role in the malaria eradication agenda.
An ex vivo gene therapy approach based on transgenic overexpression of PEDF in the eye is assumed to rebalance the angiogenic-antiangiogenic milieu of the retina, resulting in growth regression of choroidal blood vessels, the hallmark of neovascular age-related macular degeneration.
A motor neuron-specific enhancer has also been located downstream of Olig2 based on transgenic mouse studies [16].
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In antiviral biotech approaches based on RNAi, transgenic expression or non-transgenic delivery of dsRNA cognate to a target virus pre-activates or boosts the natural plant antiviral defenses.
We recognize that our comparison between PTGDS and HPGDS is based on only one transgenic mouse line for each mutant.
A method for specific detection and quantification of Roundup Ready® transgenic maize line GA21 DNA using conventional and real-time PCR and based on this transgenic sequence is described.
It is based on a transgenic mouse that expresses human CD20 (hCD20) under its own hCD20 promoter [6].
Traditionally, mouse models for human dementias are based on a transgenic approach in which human mutant proteins that cause familial forms of dementia are over-expressed under the control of brain-specific promoters [25], [26], [27].
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