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Currently, the design of crest-fixed profiled steel cladding is mainly based on time consuming and expensive laboratory tests due to the lack of adequate design rules.
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In vitro models are less time-consuming and less costly than in vivo ones, but they are still based on time-consuming and costly biological assays, being at best a medium-throughput approach.
Synthesis of new catalysts is critical for modern synthetic chemistry, but catalyst discovery is commonly based on time-consuming and frustrating trial-and-error protocols.
These studies were based on time-consuming simulations (Feder and Nosil 2010; Feder et al. 2012; Flaxman et al. 2013; Yeaman 2013) or heuristic ad hoc aproximations (Yeaman and Otto 2011; Yeaman 2013) that provide limited understanding.
However, conventional identification is based on time-consuming procedures that hamper proper management of patients with respect to antibiotic and supportive treatments.
These methods have been based on time-consuming techniques like isopycnic centrifugation with Nycodenz or Percoll [6] [9], or even complex microdissection protocols with or without enzymatic digestion [10], [11].
This method is also based on less time consuming and steps than the classical methods.
Thus, the diagnosis of AD within the clinical routine is based on a time consuming combination of psychological testing, imaging and the analysis of three well-established biomarkers (amyloid-β42 (Aβ42), total tau and phospho-tau-181) in cerebrospinal fluid (CSF) (Blennow 2005; Blennow et al. 2010; Zetterberg et al. 2010; Tapiola et al. 2009; Dubois et al. 2007).
Any solution approach based on the eigendecomposition is time consuming and hard to obtain, especially for large matrices.
However, identification based on physicochemical properties is time consuming, and the identification procedures are complex.
It demonstrates that relevance judgment mechanisms based on general knowledge are time consuming and cause the failure to solve time-constrained decision problems.
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