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The survey contained 50 items based on those utilised by previous studies.
Current, recent and previous respiratory and allergic symptoms and disease were assessed, using validated questionaries modified from the International Study of Asthma and Allergy in Children (ISAAC) [ 146] and based on those utilised by previous Raine Study follow-ups [ 32, 147] and the Busselton Healthy Ageing Study [ 35].
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Specifically, we included meta-analyses that compared the clinical effectiveness or safety of interventions (any pharmacological (including placebo and different doses), behavioural or procedural interventions) based on RCTs, utilised a Bayesian approach to conduct MTC, had at least one closed loop (see online supplementary appendix S2) and were published in full-text and in the English language.
They largely succeeded, although the system that was developed in Örnsköldsvik, Sweden, that ended up being used was based on equipment utilised by the skier instead of a true functional classification system.
In developing a system for use at the first Winter Paralympics, organisers wanted to get away from a medical classification system and use a functional system, but they ended up with a system based on equipment utilised by the skier instead.
The REGS predictors for H based on HBCCL and CGP utilised 52 and 141 genes, respectively, of which the following six were in common: CDKN2A, DPYD, GLUL, NRN1, TIMP2, and VIM.
We defined an abbreviated hospital stay as ≤1, ≤2 or ≤3 days based on values utilised in previous studies, 12 and determined the proportion of patients in this category.
Thus, based on the datasets utilised in this work, one may conclude that out of the two classification approaches (SMM and MMM) tested, the multi-label multi-class model (MMM) is robust and more apt (and should be utilised) for ligand-based target-fishing purposes – the subject matter in this study.
Although being linked with heavy peritumoural macrophage and lymphocyte infiltration based on evaluations utilising H&E slides (Klintrup et al, 2005; Richards et al, 2012a), the distinct cell types contributing to high K M score still remain equivocal.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com