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Based on clinical trial data published since then, we almost certainly underestimated the death toll.
The model assumptions were informed based on published clinical trial data and other peer reviewed studies.
Ina podcast accompanying the journal articles, Dr. Donald S. Baim, chief medical and scientific officer of Boston Scientific, called the label "artificially narrow" based on recent trial data.
Patient models are constructed based on clinical trial data and gray box system identification methods.
"Our job is to make good decisions based on clinical trial data and individualize them through our own experience and by listening to what each patient wants.
Transition probabilities and the effect of beta-blockers on mortality and hospitalization were based on clinical trial data.
The final results are based on these grouped trial data.
Leukaemia diagnoses and subclassification were based on all available data including data from national clinical trials.
They will be profiled based on this data to gauge interest, and subsequently enroll, in targeted clinical trials.
To aid in the secondary use of ImmPort data, RImmPort implements a data model based on the CDISC clinical trial data standards, and supports a suite of functions that facilitate the data retrieval.
Estimates were based on UK Prospective Diabetes Study UKPDSS) data, supplemented with data from trials and systematic reviews.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com