Sentence examples for based on this lead from inspiring English sources

Furthermore, since chlorpromazine inhibits EBOV infection, novel therapeutic modalities could be designed based on this lead compound.

Based on this lead, a series of compounds with the potential to interact with residues at the edge of the active site were synthesized and tested for inhibition of AmpC.

An industry's technological innovation will, based on this, also lead to technological progress of related industries due to the technical and economic links between them.

Based on this structural lead, we designed fluoroalkoxydihydroisoquinoline-cyclohexyl indole carbonitriles for future application as 18F-labeled tracers for SERT imaging by PET.

Actually we show an example that algorithms based on this analysis lead to approximation algorithms with performance guarantee 0.7877 and conjectured performance guarantee 0.8353 which are slightly better than the best known corresponding performance guarantees 0.7846 and 0.8331, respectively.

Further, while it is possible to think of the effect at Arg381Gln as an increased risk conferred by the common G allele, calculations of population-attributable risk based on this assumption lead to an implausibly high figure due to the very high carriage rate of the G allele in the control population.

Theoretical reasoning based on this mechanism leads to the scaling formula that the intensity of shock associated noise varies as (Mj2 − Md2)2 where Mj and Md are the fully expanded jet operating Mach number and nozzle design Mach number, respectively.

Each candidate asset was assessed to see if splitting the sample based on this predictor led to a statistically significant discrimination in life satisfaction.

An analysis of the data based on this hypothesis led to a null set, indicating that mRNAs with such anti-correlation were not observed under all conditions in this study.

A statistical analysis of bioconversion based on this mixture led to the best results of 480.10 mg of sugars/gds at 45°C, pH 3.5, and 96 hours of incubation.

The following study based on the lead compound S27847 involved modification of three regions of this compound.