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Large, well-designed RCTs and the meta-analyses based on these trials remain the gold standard.
Based on these trials new modified UF modules were installed inMarch 2004 and operated until July 2005.
Based on these trials, recombinant erythropoietin was approved for the treatment of anemia in patients with nonmyeloid malignancies in whom the anemia was caused by the effect of chemotherapy.
Based on these trials, apixaban was approved by the FDA for stroke prevention in December 2012.
Therefore, all results based on these trials should be considered exploratory (Zhu et al, 2008).
Based on these trials the clinical relevance of PUFAs in chronic heart failure patients is still not clear.
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Based on these trial simulations, the REGARD system could estimate the size of an M6-class earthquake approximately within 1 min.
Despite limitations of this study, including small sample size, statistical modeling based on these trial results suggests that a significant improvement in clinical outcomes would likely not be achieved with a larger trial.
He told the BBC: "It is certainly the most effective MS drug, based on these clinical trials, but this is definitely not a cure".
While physicians prescribe therapy and lifestyle modifications based on these clinical trials, the number of patients who follow the rules, and the percentage of patients who are actually reaching their goals (controlled their blood pressure, cholesterol, diabetes, etc)., is small.
Current recommendations are based on these later trials, favouring a high peak serum concentration using high doses of aminoglycoside as boluses and close monitoring of residual serum concentrations to avoid renal toxicity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com