Then based on these pre-determined sensing sets, SUs will perform spectrum sensing and run the underlying MAC protocol to access the channel distributively in each cycle.
Initial judgments based on these pre-existing constructs in relation to the context of the new case, lead to the construction of a frame 17 that limits and gives direction to the rest of the cognitive process.
Furthermore, based on these pre-clinical findings, a complete clinical research program was developed in order to establish the utility of the biomarkers for the early diagnosis of sepsis.
This approach would require only minor adjustment to the currently used clinical expansion protocols, and thus clinical testing would be simple, and appears justified based on these pre-clinical studies.
A prospective randomized phase II study assessing the impact of adding selumetinib to docetaxel in previously treated patients with advanced KRAS mutant NSCLC was conducted based on these pre-clinical results.
Based on these pre-clinical results, and using doses identified in phase 1 clinical trials of retaspimycin HCl monotherapy, a phase 2 clinical trial was initiated to evaluate the efficacy of retaspimycin HCl plus trastuzumab in patients with advanced HER2+ metastatic breast cancer progressing on prior trastuzumab therapy.
Based on these encouraging pre-clinical activities, AT7519 is currently in clinical development.
Based on these results, a pre-treatment step was added to the resin packing protocol.
The predictive models developed were able to assign a positive or negative clinical outcome to each patient based on these five independent pre-treatment variables, with an accuracy of 69.4% and 79.3%, respectively.
Based on these observations, heavily pre-treated metastatic melanoma patients were treated with lympho-depleting chemotherapy, consisting of high-dose cyclophosphamide and fludarabin, followed by infusion of large numbers of TILs (around 1 × 10 cells) followed by bolus infusion of high-dose IL-2 (up to 15 boluses) [30,60].
