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This strategy maps quantitative trait loci that are imprinted (i.e., iQTLs) based on their segregation and transmission across different generations.
These SNPs were used to develop a linkage map based on their segregation patterns among the 100 RILs.
This initial screen also allowed us to identify markers that would likely map to the d2 region based on their segregation pattern in the four recombinant lines.
We focused on validating Category 2 SNPs due to their suitability for mapping in tetraploid alfalfa based on their segregation patterns in this population.
However, the amount of distortion was likely underestimated, because we initially selected loci to map based on their segregation profile and markers not meeting that criterion were not included in building the map.
To minimize software-induced map inflation (Table 2), we collapsed the 1,546 'bPb' markers into 959 bins based on their segregation signatures concatenated across populations and used moderately stringent program settings to assemble a DArT skeleton bin map with JoinMap (LOD = 2; REC = 35).
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Fifteen variants causing amino acid changes were selected based on their co-segregation pattern within the family (Table 1).
In QTL mapping, we use known (observable) marker information to infer unknown (unobservable) QTL genotypes based on their co-segregation in a population.
These markers were selected based on their quality and segregation in the analyzed progenies for at least one parent.
Leaders of the civil rights movement made a case against segregation based on their view that all human beings, as created by God, have equal rights.
The microtubule system, a major component of the cytoskeleton, was identified as a suitable target for cancer therapy, primarily based on their biological importance in coordinating chromosome segregation during mitosis.
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based on their phenotype
based on their feedback
based on their ninja
based on their firing
based on their oil
based on their success
based on their experience
based on their position
based on their history
based on their median
based on their gender
based on their morphology
based on their judgement
based on their response
based on their fitness
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