Sentence examples for based on their mutation from inspiring English sources

Since 24 factorial combinations are present, there were 276 possible ways of grouping the mice into two groups based on their mutation status, genetic background, diet and sex.

This cutoff differs across cancer types based on their mutation level.

Selection of the gene regions was based on their mutation frequencies, based on the COSMIC database (Table  1).

Three genes (HSPG2, CELA1, and KCNK5) were nominated as related to the pathogenesis of BEN based on their mutation frequency, their similar incidence in both Bulgarian and Serbian patients' groups, lack of information about the established variants in European population, and nonincidence in healthy Bulgarians.

Recent analyses (Bell et al, 2005) of phase II and III trials for EGFR-TKI, in which patients were not selected based on their mutation status, have suggested that EGFR mutations are correlated with response to therapy but are not correlated with overall survival (OS).

Based on their high mutation frequency, SLC35F5, ARV1, TTC3, and SMAP1 represent new target genes in which frameshift mutations have not previously been reported in MSI CRC.

Fifteen autosomal recessive deafness genes were selected, based on their reported mutation frequency (Table 1) [ 4].

Some patients in our database might have been treated with these newer agents (monoclonal antibodies against growth factors, and tyrosine kinase inhibitors) based on their tumor mutation profile.

In this study, we stratify breast cancers based on their TP53 mutation status and identify the set of dysregulated tumorigenic pathways and their candidate driver genes by using gene expression data sets obtained from tumours.

In this study, we stratify breast cancers based on their TP53 mutation status and identify the set of dysregulated tumorigenic pathways and corresponding candidate driver genes using breast cancer gene expression profiles.

Thus, even among patients who are selected based on their EGFR mutation status, men or smokers may still be at risk for developing ILD; therefore, biomarkers to predict ILD are needed.