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Based on their intense, homogeneous, and, most importantly, stable expression of ACE2 over various passages, we chose the 2B4 clone to explore the innate epithelial signaling pathway/s elicited by SARS-CoV by microarray-based functional genomics.
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Based on their stable and intense ACE expression and, thus, enhanced permissiveness to productive SARS-CoV infection, compared to that of parental Calu-3 cells (Figure 1), we chose the cloned 2B4 cells for studying the temporal expression of airway epithelial genes related to the innate antiviral defense against SARS-CoV infection by using microarray-based functional genomics.
Many specific cases warranted intense investigation, based on their compelling clinical presentations, the likelihood that the basic defects would be uncovered and the impact predicted to emanate from the 'new disease discovery'.
During the consensus meeting, the observers concluded that in some cases vascular wall uptake was considered to be less intense than liver uptake based on their first impression that large-vessel vasculitis was not present.
The relationship between job polarization and business cycles is the subject of intense debate based on apparently mixed evidence.
It's an almost unheard-of situation, and one based on an intense level of devotion on her friend's part.
In this work we develop a complete set of technical specifications and test procedures that have been designed within the frame of the UTSfSHS, based on an intense review of the scientific and technical publications related to LED lighting and their practical application.
The reason is the camera's light meter is setting itself based on the intense sunlight in the background.
The method was based on the intense fluorescence (250/410 nm) observed after a UV photochemical treatment of cyclofenil.
"I think it is a very different situation," said Ms. Menin, who is running for Manhattan borough president and said her opposition to the earlier trial was based on the intense disruption that security precautions would have brought to the neighborhood.
If published, a fourth novel in the series would almost certainly be a best seller, based on the intense interest in the first three books about the computer hacker Lisbeth Salander and the journalist Mikhael Blomkvist.
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