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From here, users could select one of the binding positions of interest based on their conservation in the "Alignment View," and click on "Design MREs" button on the left of any sequences in the group for trying the MRE design step as described in the design tool section.
One criterion for microRNA identification is based on their conservation across species, and prediction of miRNA targets by empirical approaches using computational analysis relies on the presence of conservative mRNA 3′UTR.
Based on their conservation and diversity, the 54 T cell epitopes formed three groups: Seventeen (17) T cell epitope sequences of the 2003 strain (11 PB1, 4 PB2, and 2 M1) were conserved in at least 88% of all recorded human and avian influenza strains (Table 4).
In a system such as the S. alburnoides complex, in which no genomic information is available, our strategy was to isolate potential candidates for sex determination and assess, based on their conservation, functional characteristics and expression patterns whether they could have a role in the establishment of the phenotypic sex.
To access the role of the PcG in Notch-1 regulation, we performed a bioinformatic analysis of the Notch-1 promoter to delineate regions of interest based on their conservation, CpG content, and position relative to the transcription start site (TSS).
The identification of introns in E. cymbalariae was mainly based on their conservation within homologous genes.
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In order to enhance our understanding of miRNA evolution, diversification and function, we classified all known soybean miRNAs based on their phylogenetic conservation (conserved, legume- and soybean-specific miRNAs) and examined their genome organization, family characteristics and target diversity.
As some of these loci may have been selected for further experiments based on their evolutionary conservation, we note that they are potentially biased toward more conserved sequence.
Using discriminant analysis, three groups of farmers were identified based on their soil conservation efforts.
(Although the state seeks to cut urban water use by 25% overall, different areas have higher or lower goals based on their past conservation efforts).
This, however, is due to the fact that many annotated miRNA were first identified based on their sequence conservation [ 1, 8, 12].
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based on their resources
based on their ninja
based on their lack
based on their success
based on their experience
based on their race
based on their year
based on their position
based on their history
based on their post-mortem
based on their gender
based on their judgement
based on their yield
based on their fitness
based on their counter-subversion
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