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By combining both backscattered and fluorescent light from different timepoints, we devised a strategy for visualizing the entire PR RPE CC complex based on the uptake of ICG dye combined with high-resolution retinal imaging enabled by our custom-built multimodal AO retinal imager.
Using the classification based on the uptake ratios, discrepancies to visual evaluation could be found in a comparable frequency, resulting in a correspondingly fair agreement.
The multiparametric apoptosis kit quantifies three fundamental parameters related to the process of apoptosis, i.e. (i) nuclear condensation, detected by the blue fluorescent nuclear dye, Hoechst 33342; (ii) F-actin content, detected by green fluorescent Alexa Fluor ® 488Phalloidin stain; (iii) mitochondrial membrane potential, based on the uptake of MitoTracker ® Red into mitochondria of cells.
However, for studies on trans-differentiation, such as mesenchymal or hematopoetic stem cells differentiating to cells of other tissue like neurons or epithelial cells, interpretations based on the uptake of the label can be misleading especially since a very low percentage of cells are thought to change lineages and this may well be from the macrophage uptake of labels [45] [46].
This report analyses our experience with a combination of [F]FDG-PET/CT and [Ga]DOTATOC-PET/CT in 20 patients with pulmonary carcinoids to assess the possibility of differentiating the 2 histopathologic variants based on the uptake patterns.
In many micro-organisms as well as in higher plants the metabolism of sulphur is based on the uptake and subsequent reduction of oxidised, inorganic sulphur compounds, usually sulphate.
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The basal [H]-D-Asp uptake data are based on the measured uptake in the chemotherapeutic-cells normalized to that in the relevant parental cell line on the experiment performed in duplicate.
The alternative test is based on the fuel uptake rate and image analysis, rather than the height of the flame.
In addition to the brain surfaces, we applied the deformable model for extraction of the coarse cortical structure based on the tracer uptake from FDG-PET brain images.
Fifty-nine lesions were found to have SUVmax above the threshold based on the liver uptake as measured on the OSEM images.
These values are based on the weekly uptake in foods, wherever useable data or studies were available, as well as the median and arithmetic mean of aluminium content.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com