Liquid mixing was studied based on the tracer-response technique, using the model of axial dispersion.
Cross-type APTV pulse data were eventually analyzed to determine dispersion coefficients based on the tracer curves.
In addition to the brain surfaces, we applied the deformable model for extraction of the coarse cortical structure based on the tracer uptake from FDG-PET brain images.
Its mechanism of uptake is based on the tracer's sequestration within the mitochondria of living cells, which can be applied as well on oncological imaging such as scintimammography [31].
Formerly, the accumulation time of a typical brain FDG-PET study ranged from 45 to 60 min, when the regional uptake reflects glucose metabolism based on the tracer kinetics [29], which is necessary for quantitative measurement of glucose metabolism.
PET is based on the tracer principle for imaging.
Based on the tracer kinetic model, developed by Georg von Hevesy early last century, nuclear medicine techniques involve administration of 'radiotracers' in minute amounts in order to mimic the fate of related, non-radioactive chemicals.
Then, based on the tracer distribution in space and time, radiation dose is calculated using phantoms, i.e. computational models that mimic organ geometry, organ-to-organ distances, and body composition of patients.
The methodology for delineating glycocalyx barrier properties, which was used in the current and previous studies [ 21, 24- 27], is based on the tracer dilution technique, with the choice of tracers being inferred from intravital microscopic observations of intravascular tracer distribution in cremaster capillaries [ 36- 38] and in mesenteric blood vessels [ 39, 40].
We also find excellent agreement in the amount of dust present and dust accretion rates based on the two tracers at the 300 ka site and the 1120 ka site, respectively.
