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Different pharmaceutical companies have developed their respective question- and/or risk-based approaches for TP-DI based on the TP mechanism of action as well as patient population.
Concretely, based on the TP model transformation and an ad hoc rectification, a well-adjusted polytopic representation is acquired for the nonlinear system by two independent steps, where the first step guarantees the satisfactory representation error, while the second step further assures the tightness of the vertex polytope.
A number of statistical metrics, commonly used to evaluate the performance of diagnostic tests, can be calculated based on the TP, FP, TN, and FN values, e.g., specificity, sensitivity, accuracy positive predictive value (PPV), and negative predictive value (NPV) (Table II) (10, 11).
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A total of 216 samples encompassing six dense graded asphalt mixes were tested at three temperatures with four replicates per mix type using static semicircular bending test based on the AASHTO TP 105-13 protocol.
Based on the average TP concentrations, the trophic classification system for tropical lakes (Salas & Martino, 1991) assigns the Nyanza Gulf to a hypereutrophic state.
Therefore, our estimation of the number of true positive (TP*), false positive (FP*), and false negative (FN*) for the undefined orthogroups based on the number of TP, FP, and FN calculated from the defined groups seems to be valid and our results should be representative of the entire population of orthogroups present in the six yeast genomes under study.
Based on the facts that TP locusts showed higher aerobic respiration rates than the NP locusts under extreme hypoxia and the aerobic metabolic processes were not as severely suppressed in TP locusts as in NP locusts, we speculate that the aerobic metabolism plays an important role in the adaptation of TP locusts to extreme hypoxia.
In the first and second levels, i.e. nucleotide and binding site levels, sensitivity, specificity, performance coefficient and F-measure are computed based on the true positive (TP), false positive (FP) and false negative (FN) information gathered by comparing the predicted and actual binding sites.
The tissue responses within and across both stages were reproducible, based on the decreases in TP-stimulated tissue weights relative to the TP-stimulated control from the eight individual laboratories, as illustrated by the VP results.
The tissue responses were reproducible within and across stages 1 and 2 and were consistent based on the decreases in TP-stimulated tissue weights relative to the TP-stimulated control from the eight individual laboratories, as illustrated by the VP results.
Based on the idea that the TP was gradually uplifted from south to north, they assumed that the central southern TP was uplifted first, followed by the Himalaya, the northern TP, and then the Mongolian Plateau.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com