We did pre-specified χ tests of the study comparators and endpoints based on the supplement category, chemical type, therapeutic area, and orphan drug status.
‡ Based on the March Supplement to the Current Population Survey, 2002.
Lastly, the prevalence of use of any type of VM or NVNM supplement, including more mainstream daily multiple vitamins and calcium, was more than three times greater than the prevalence of herbal use based on the coded supplements.
Further broadening to use of any NVNM or VM other than multivitamin and/or calcium resulted in a percentage twice as high as herbal use based on the coded supplements.
The supplements in the GEN arm of the GD study were provided by Springfield Nutraceuticals (Oud-Beijerland, the Netherlands) based on the commercially available supplement Mega Soja with an isoflavone content of 25 mg daidzein, 21 mg genistein and 5 mg glycitein per supplement (aglycone equivalents, Table 1).
Accordingly, the majority of CHMs for recurrent miscarriage in this review were prescribed based on the principle of supplementing the spleen and kidney.
Power to detect a difference in the prevalence of anemia was computed based on the available number supplemented and non-supplemented children in the dataset and the prevalences of anemia found in the two groups.
Therefore, we used two realistic high-intake scenarios of dietary supplements based on the limited Dutch dietary supplement data available: one for adults (≥18 years old) and one for children (1 17 years old).
The structure of the training program was based on the ACTIVE trial supplemented by previous reports of effective training, and the contents were adapted for Hong Kong Chinese elderly.
The osteogenic differentiation medium was based on the expansion medium supplemented with 10 nM dexamethasone, 0.1 mM ascorbic-acid-2-phosphate and 10 mM β-glycerophosphate.
