AEs (including adjudicated CV events), laboratory parameters, and vital signs will be reported descriptively, based on the safety population (all randomized patients who received at least one dose or partial dose of study treatment).
Safety assessments were based on the safety population, which included all patients who received at least one dose of study medication.
All safety and tolerability assessments were based on the safety population, defined as all subjects who received at least one dose of study material.
Safety analyses were based on the safety sets defined as all patients who received at least one dose of the study medication and had at least one follow-up safety assessment.
Safety analyses except renal function were based on the safety population, which included all randomized patients who received at least one dose of study medication.
Patient demographics, baseline characteristics, and safety/tolerability analyses were based on the safety population, defined as all randomized participants who received at least one dose of study drug.
And some major insurers have started adjusting prices based on the safety performance of vehicles.
"But there is other long-established law that says the decision is supposed to be based on the safety and efficacy of the drug".
If a family is making a choice based on the safety data between an Explorer and a van -- say a Dodge Caravan or Ford Windstar -- it would pick the van, which has lower fatality and rollover rates.
"It was a judgment decision based on the safety of a lot of market participants, especially as the storm seems to be getting more severe," Lawrence E. Leibowitz, chief operating officer of NYSE Euronext, told Bloomberg News.
In the 1960s and 1970s, when the commission and a predecessor agency, the Atomic Energy Commission, issued construction permits for the 104 commercial reactors now running, they established requirements for hardware and training based on the safety factors arising from the characteristics of each site, including its vulnerability to flood or earthquake.
