Sentence examples for based on the risk reduction from inspiring English sources

The requirement is defined as safety integrity level (SIL) based on the risk reduction concept for protection layers, from original process risk to tolerable risk level.

In addition to comparing within-trial clinical outcomes, we will model the projected changes in life expectancy and cardiovascular outcome rates that would be seen with lifelong use of the drug, based on the risk reduction rates seen in the trial as well as baseline observational data from the three countries where the trial is being conducted (Scotland, Ireland and the Netherlands).

Spain is a Mediterranean country with low cardiovascular risk, and perhaps the Spanish physicians prescribe drugs based on the absolute risk reduction rather than on the relative risk reduction; although we must not exclude the possibility of a low market penetration of these drug treatments.

In cases in which a credible trial for a particular dose existed, the pleiotropic effect was calibrated directly based on the disease risk reductions observed in the trial.

The efficacy of therapy is estimated based on the proportional risk reductions that which were obtained from meta-analyses of the effectiveness of adjuvant therapy and from the data published or presented from individual randomized clinical trials [ 6].

Decisions should, in line with expected utility theory [ 5], be based on the absolute risk reductions (or its reciprocal NNT) even though this principle in practice is frequently violated.

In that study, the criterion for treatment failure was based on fasting plasma glucose > 10.0 mmol/l [corresponding to an HbA1c of approximately 64 mmol/mol (8.0%)] and, based on that criterion, the risk reduction in the cumulative incidence of treatment failure with rosiglitazone vs. metformin was approximately 30%.

The agency said in a new report issued today that a more pro-active approach based on the principles of risk reduction is needed to build greater resilience to droughts.

Screening-naive and previously screened subjects equally preferred 5-yearly FS and 10-yearly TC (P=0.24; P=0.11), but favoured both strategies to annual FOBT screening (all P-values <0.001) if, based on the literature, realistic risk reduction of CRC-related mortality was applied.

Instead, it should be based on the reduction of risk achieved through the lowering of the concentration of the dissolved constituents emanating from the entrapped NAPL during source zone clean-up.

The required information size was calculated based on a relative risk reduction of 15% in mortality and overall morbidity and a relative risk reduction of 50% in myocardial infarction.