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Our study revealed that people older than 60 years with confirmed diagnosis of hip and knee OA are at an increased risk of falling based on the prolonged TUG test time, which strongly correlated with weak muscle strength of the lower extremities, evaluated using 30 CST.
Metronomic chemotherapy is a frequent (even daily), prolonged low dose administration of a chemotherapeutic drug, thus we have decided to design our study based on the prolonged oral administration of tegafur at a fixed dose of 100 mg twice a day which is approximately one third of the published, standard, daily total dose.
This slightly accelerated degeneration may be based on the prolonged light period (14 h instead of 12 h) and slightly increased light levels in our new animal facility.
The first possibility can be excluded based on the prolonged stability of our device performance achieved without replenishing methanol in the electrolyte, which would be impossible if methanol served as a sacrificial donor.
The strategy to achieve resistant parasites was based on the prolonged exposure of parasites to consecutive small increments in drug doses in treated mice over many generations.
In other words, based on the prolonged enhancement in liver parenchyma, this new contrast agent has potential in further diagnostic and therapeutic application by carrying tumor markers or therapeutic drugs.
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Importantly, based on the CIx values, prolonging the exposures resulted in a shift of classification of chlorpromazine from having a low cholestatic risk after 8 days to having cholestatic risk after 14 days, thus emphasizing the value of performing long-term, repeated exposures.
A majority of tropical plants bear fruit in rainy seasons and the fruiting period is shortened or prolonged based on the precipitation of the current season (Bawa and Hadley 1991).
Based on the results, we think this prolonged recovery time is clinically acceptable.
It is based on the assumption that complications often prolong the patient's hospital stay.
We developed an outcome indicator based on the finding that complications often prolong the patient's hospital stay.
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