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It focuses on human thermal comfort based on the physiologically equivalent temperature (PET) for different species.
The assessment of thermal comfort was based on the Physiologically Equivalent Temperature (PET), calculated using the RayMan model.
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Arterial pressure waveform analysis is based on the physiological principle that stroke volume is physiologically related to the arterial pressure wave and aortic impedance.
We conclude that subunit exchange experiments conducted at 25 °C do reflect tafamidis-associated stabilization nicely but suggest that studies for selecting doses of tafamidis for various TTR genotypes should be conducted at 37 °C to ensure that such critical patient-centered decisions are based on the most physiologically relevant data possible.
In this study we have verified that MEG inversions based on the beanformer give physiologically reasonable trajectories of source peaks consistent with V1 retinotopy.
A PBPK provides an approach to modeling drug distribution and metabolism that is based on the use of a physiologically realistic model of the animal.
The observed increase of MEF2D protein expression following rotenone exposure prompted us to clarify the intracellular localization of this increase, based on the evidence that MEF2D physiologically translocates from the nucleus to the cytosol for its degradation.
As presented previously, the MBL concentration was measured using an in-house time-resolved immunofluorometric assay based on the recognition of a physiologically relevant ligand combined with detection by a specific monoclonal antibody (11).
Based on the concept that MV should mimic physiologically noisy breathing patterns, biologically variable or noisy MV was introduced, which attempted to mimic spontaneous breath-to-breath variability during volume-controlled MV [ 2].
Subsequently, one at a time, the values of each system-specific parameter were increased with a physiologically relevant value based on the mean increase in each age group.
Examples are presented to show the feasibility of predicting changes in toxicokinetics of the components of complex chemical mixtures based on the incorporation of binary interaction data within physiologically based models.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com