The application is based on all the notified cases with information derived from both the patient's physician and the laboratory, having diagnosed the causative agent.
The estimations for medicines are based on the 125018 cases notified to WHO in 2005; 203564 cases notified in 2006; and 110837 cases notified in 2007 [ 8].
The probability of adequate clinical samples being obtained for notified cases was modelled using a beta distribution based on the proportion of notified cases for each jurisdiction between 2000 and 2005 that had two stool samples submitted for analysis within the recommended time frame, and the number of AFP cases notified by each jurisdiction over the same period.
Figure 1 shows the annual incidence of gonorrhoea based on the number of cases notified to the NBH since the year 1900; the years of major amendments on legislation (1906, 1947, 1973, 1988) and changes of the clinical notification system (1980 , 1994 are indicated.
All information in the database is derived from the notifications, and the data (including "country of infection") are thus based on the best judgment of the notifying clinician based on the patient history and knowledge of the characteristics of the pathogen in question.
The purpose of the FC is to output a global spectrum decision, based on the sensor reports, to notify SUs if they can access a licensed spectrum band, in accordance to the FCC statutes.
The data is based on all notified cases, regardless of country of infection.
Therefore, we also calculated case finding percentages based on all notified partners with an STI test result (irrespective of the STI that they were at risk for/notified for).
Older patients were not recruited, since a low pH1N1-incidence was expected among them based on the age distribution of cases notified in Germany at the time the study was planned (<1% of cases aged >60 years [ 6]).
The lowest estimated incidence of adult dengue death was 6.8 per 10,000 dengue cases, based on 41,234 notified dengue cases over this period [ 13] (potential dengue deaths outside of the five hospitals and those diagnosed with dengue serology were not included).
