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Based on the mutations' effects, a signal from the hormone seems to be a key trigger of puberty, the researchers report online today in Nature Genetics.
Based on the mutations, the researchers think that a common ancestor of the birds lost the enamel caps on its teeth around 116 million years ago.
Haplotypes were inferred by the PHASE program [34], [35] based on the mutations discovered by sequencing.
Other labs provide references and treatment recommendations based on the mutations identified.
Fearon and Vogelstein (1990) first proposed a temporal ordering of mutations based on the mutations in colorectal tumors from different stages.
Based on the mutations' prevalence we estimated that three different tumor regions should be sampled to detect mutations in PBRM1, SETD2, BAP1, and/or KDM5C with 90% certainty.
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The first step of the algorithm involves assigning each sample to one of two cohorts based on the mutation status of the investigated gene.
Based on the mutation data and CoMFA model, a multiply mutated octapeptide S24 was designed for higher activity.
Based on the mutation type, the combinatorial effects of two mutations or of one mutation with the wild-type protein can set the course of the disease and generate a mild to severe gradient of symptoms.
Although the mutation was heterozygous, he was diagnosed with CTLN2 based on the mutation, recurrent symptoms, hyperammonemia, and hepatic encephalopathy.
MitoKor is creating a diagnostic test based on the mutation assay.
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