Sentence examples for based on the mutation from inspiring English sources

The first step of the algorithm involves assigning each sample to one of two cohorts based on the mutation status of the investigated gene.

Based on the mutation data and CoMFA model, a multiply mutated octapeptide S24 was designed for higher activity.

In the latter step, the statistical confirming procedure, the two lists of possible OGs and TSGs undergo four tests to assess whether the mutational pattern in each gene shows statistically defined evidence of positive selection based on the mutation rate and the number of non-silent mutations, calculating their statistical probability of being true driver mutations.

Based on the mutation type, the combinatorial effects of two mutations or of one mutation with the wild-type protein can set the course of the disease and generate a mild to severe gradient of symptoms.

Based on the mutation rate in modern humans, the team approximated the age of the Siberian girl at about 80,000 years.

A second analysis was conducted to compare the performance of the models after 10 years based on the mutation status of the BRCA1 or BRCA2 genes.

Based on the mutations' effects, a signal from the hormone seems to be a key trigger of puberty, the researchers report online today in Nature Genetics.

Electronic medical records are scoured and run through algorithms designed to help doctors pick the best cancer treatments based on the mutations in patients' tumors, for example, or to predict their likelihood to respond well to a treatment regimen based on past experiences of similar patients.

Based on the mutations, the researchers think that a common ancestor of the birds lost the enamel caps on its teeth around 116 million years ago.

Haplotypes were inferred by the PHASE program [34], [35] based on the mutations discovered by sequencing.

However, the degree of this influence should vary among cells based on the mutation-generated phenotypic diversity of cells.