Sentence examples for based on the multifactorial from inspiring English sources

In particular, it has been argued that the recommended two-tier approach is not evidence-based, and that it does not offer the best quality of treatment based on the multifactorial pathophysiology of T2DM and the need for individualized therapy [24].

Based on the multifactorial nature of AD, preparation of multi-target-directed ligands presents a viable option to address more pathological events at one time.

We used the Raven Colored Progressive Matrices Test, standardized for Brazilian children, which assesses general aspects of nonverbal intelligence, based on the multifactorial theory of Spearman [ 15].

CBC is an intervention based on the multifactorial integrative model of depression by Lewinsohn and colleagues [ 17], which considers depression as the outcome of behavioral, cognitive and emotional changes initiated by the environment and moderated by cognitive factors.

Further, our analysis of relative genetic and environmental contributions was based on the multifactorial liability model, and our results are subject to assumptions, so should be interpreted with caution.

The current understanding of the origin of schizophrenia is mainly based on the multifactorial-threshold (MFT) model of genetic liability and the neurodevelopmental model [ 1].

The classic drug-design strategy based on the "one-molecule-one-target" paradigm was found to be ineffective in the case of multifactorial diseases like AD.

Thus, in our previous paper [ 11], we carefully re-examined the necessary conditions for putative nuclear susceptibility genes for SCZ and deduced a criterion (the persistence criterion, or 'P-criterion') for nuclear susceptibility genes for SCZ based on the general assumptions of the multifactorial threshold model.

We conducted a prospective study with a multifactorial approach based on the population-based longitudinal Swedish Adoption/Twin Study of Aging (SATSA).

Although Golub et al. acknowledge the multifactorial causes of obesity, their hypothesis seems to be based on considering fish oils to be a "magic bullet" public health solution (12).

This is based on the original approach to complex multifactorial disorders proposed by Falconer (1965), and subsequently developed to contrast different models of comorbidity by Neale and Kendler (1995).