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Our approach offers a new tool for the investigation of the biochemical composition of tumour milieu and for development of novel therapies based on the modulation of extracellular purine-based signalling.
The molecular response of plants to abiotic stresses has been often considered as a complex process mainly based on the modulation of transcriptional activity of stress-related genes.
In this report, we describe the synthesis of a novel library of α7 nAChR ligands based on the modulation of the quinuclidine, quinazoline and tropane moieties.
Protective autoimmunity is a physiological process based on the modulation of inflammatory cells that can be boosted by immunizing with neural-derived peptides, such as A91.
A highly speculative attempt is made to show that this optimum condition based on the modulation of magnetic energy may have significant contributions from the self-sustained fusion processes in the energy generating region at the center of the Sun.
In this review, after a short historical preface, we describe the current model of chemosensory transduction based on the modulation of membrane K+ channels by O2 in specialized chemoreceptor cells.
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It bases on the modulation of the spatial coherence of the optical field in amplitude and phase.
As compared to the DAO algorithm, our method has an efficient form of quadratic optimization, with an additional advantage of optimizing field-specific numbers of segments based on the modulation complexity.
Its title revealed a program of research based on the specific modulation of receptors by organic molecules, the behavior of which in the body could be monitored, understood, and exploited.
The aim of this research was to develop the non-invasive technology for the generation of a new type of flax based on the epigenetic modulation of nucleic acids.
The agent contains tegafur (FT), 5-chloro-2,4-dihydroxypyridine (CDHP) and potassium oxonate (Oxo) in a molar ratio of FT : CDHP: Oxo=1 : 0.4 : 1, based on the biochemical modulation of 5-FU (Shirasaka et al, 1996a, 1996b).
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