Sentence examples for based on the modeled from inspiring English sources

3) The newly designed adamantane-based inhibitors based on the modeled structure of H1N1-M2 proton channel have two pharmacophore groups, which act like a "barrel hoop", holding two adjacent helices of the H1N1-M2 throughr theough two two pharmacophore groups outside the channel.

To get an idea of how much the various mutations would affect the overall structure of the Spy-client complex we show below a complex model based on the modeled structure of a theoretical Spy variant that contains all four of the key activity-enhancing mutations (Q49L, H96L, Q100L, F115L) and modeled its binding with the Im7 7-45 peptide.

Based on the modeled acetate and butyrate profiles, modeled H2 profiles shown in Fig. 5 were calculated in a similar manner as the theoretical H2 shown in Table 4, with 848 ml H2 g−1 acetate and 578 ml hydrogen g−1 butyrate (from stoichiometry of Eqs. 2 and 3), and 1.067 g COD g−1 acetate and 1.82 g COD g−1 butyrate.

The fatigue life predictions based on the modeled crack-opening stresses and the fatigue notch model were in good agreement with the experimentally determined fatigue data.In the interest of simplifying the use of crack-opening stress in design, the average crack-opening stress was correlated with the frequency of occurrence of the cycle reducing the crack-opening stress to the average level.

The structural basis of all of the known Jak3 mutations reported so far is discussed based on the modeled structure.

To determine the distributions for the waiting phase based on the modeled mobility and routing, we consider the periodic forward attempts employed by LAROD.

Then, the initial modeled background frame B ^ t (t = 2,3,…,19) is obtained based on the "updated" modeled background frame B t 1 (see Section 2.3) and the block motion representation frame R ^ t.

Based on the aforementioned modeled behavior, a method of generating the eggs is required and will be applied with the LF.

Based on the preliminary modeled compositions of these factors, we interpret that there may be one intermediate crustal source, and at least one dacitic source exhibiting higher Ti/Al ratios, although we cannot differentiate further based on QFA alone.

Hence, based on the literature, modeled scenarios and field experience, the authors discovered it is much easier for individuals to drive this transition to 100% renewable energy than to continue to depend on government forever.

We also demonstrated that structural optimization can further improve the peptide affinity by site-directed mutagenesis of selected residues based on the computationally modeled complex structure of TGF-β with the cyclic peptide.