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Gene networks were constructed based on the Ingenuity knowledge base.
Disease information is based on the Ingenuity knowledgebase (Ingenuity) and Genecard http://www.genecards.org/.org/
The criteria are based on the ingenuity knowledge base and on our statistical filters as described above.
The tool "Path Explorer" was used to search for documented molecular interactions based on the Ingenuity® Knowledge Base.
The analysis is based on the Ingenuity Pathways Knowledge Base repository collected from the full text of the peer-reviewed literature in life sciences.
IPA is a software used to connect molecules based on the Ingenuity Knowledge Base, its database of information on biomolecules and their relationships [ 19].
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Creative family - based on the inventiveness, ingenuity and inspiration of people engaged in the process [36, 37].
The families are described alphabetically: i) Creative family - based on the inventiveness, ingenuity and inspiration of people engaged in the process [36, 37].
Based on the curated Ingenuity Knowledge Database and using a right-tailed Fisher's Exact Test, overrepresented functions and pathways associated with intersecting gene lists were identified and the significance of association (p-value) was calculated based on the probability of pathway assembly from a random set of genes of the same size as the input list.
For genes with a human ortholog, further interpretation was based on the use of Ingenuity and Gene Ontology annotation databases highlighting several biological processes likely to be involved in muscle glycogen regulation.
The networks are ranked and scored based on the number of the Ingenuity Knowledge Base Network Eligible molecules they contain.
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