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Because energy metabolism is being recognized as a/the critical pathway regulating the immortalization-to-senescence transition, metformin-based therapies based on the induction of senescence would prevent the generation of CSCs.
Therefore, we estimated the activation of mp53 based on the induction of WAF1 which is one of downstream factors regulated by p53.
The activity of AGE-preparations was confirmed using the one stage clotting assay as previously described[ 19], which is based on the induction of tissue factor on the surface of endothelial cells.
An interesting example of a vaccine against chronic diseases based on the induction of self-antigen-specific antibodies.
The method is based on the induction of the bioluminescent activity of genetically manipulated mammalian cells.
Many vaccines developed against these diseases remain, similar to classical vaccines, based on the induction of antibody responses.
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Grape transformation methods based on the induction and selection of somatic embryos are comparable in length [ 10].
The understanding of these mechanisms is essential for the outcome of regenerative therapies of diabetes based on the induction duct cell proliferation and differentiation.
Seasonal influenza vaccines are licensed based on demonstrating the induction of HI antibody titers above a defined threshold; a HI antibody titer of 1 40 is generally accepted as corresponding to a 50% reduction in the risk of influenza, which is based on a challenge study conducted forty years ago [ 40].
Tomato is physiologically classified as a climacteric fruit based on the dramatic induction of respiration and ethylene at the onset of ripening.
Based on the observed induction of signalling pathways, we have screened for the ability of 3T3-L1 and mammary adipocytes to release cytokines/chemokines and growth factors.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com