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Based on the indispensible role of hsp90β1 in PIMCE [17], it is expected that hsp90β1 would be essential for LA-induced peroxynitrite generation if the peroxynitrite response of LA indeed depends on [Ca2+]m efflux in HM cells.
In addition, Perissi et al (2008) provided evidence that dedicated strategies based on the indispensible actions of TBLR1 were adopted by NF- κB-regulated genes in Hela cells.
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