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The diagnosis was made based on the endoscopic finding of a tumor within a diverticulum [7].
We emphasize that, based on the endoscopic findings, these colonic and gastric metastatic lesions essentially had the appearance of hyperplastic polyps.
If the diagnosis based on the endoscopic images was HGIN or ESCC (that is grade I), while the histopathological diagnosis based on the biopsy was LGIN or MGIN, ER was performed after consultation with patients.
Based on the endoscopic and intraoperative findings, the most common mechanism of perforation was determined to be direct trauma from the shaft of the endoscope (n = 6, 40%), and followed by trauma from the tip of the endoscope (n = 5, 33%).
For CD patients disease activity in the rectum was graded by the endoscopist based on the endoscopic appearance as "remission" if no visible lesions were seen, as "mild activity" if erythematous mucosa and/or erosions of the mucosa were seen but with no ulcers in the rectum and as "severe activity" if ulcerations or spontaneous bleeding were found.
The diagnosis of CD was made based on the endoscopic, radiological, histological, and clinical criteria established by both the World Health Organization Council for International Organizations of Medical Sciences and the International Organization for the Study of Inflammatory Bowel Disease [ 16, 17].
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Endoscopic scoring of colitis activity was based on the murine endoscopic index of colitis severity scoring system that includes classification of mucosal translucency, vascularity, granularity, fibrin deposition and stool consistency (36).
Based on the above endoscopic findings, this lesion was diagnosed as an adenoma, which is a good candidate for endoscopic local resection.
The depth of the lesion was predicted as submucosal (sm) invasion based on the conventional endoscopic findings because of the fold convergence and the reddish depressed area.
The macroscopic classification was based on the Paris endoscopic classification [ 2, 3], classified as 0-IIa, 0-IIb, 0-IIc, to distinguish the invasive from non-invasive lesions.
We suggest that the definition of BE should be based on the clinic, endoscopic, and histological findings rather than the pattern of CK7/20 immunostaining.
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