Based on the limited availability of efficacious or cost-effective diagnostic tests, the American College of Obstetricians and Gynaecologists recommends routine yearly gynaecological examination with further evaluation limited to patients presenting with bleeding or vaginal discharge [ 18].
Based on the probabilities of being most efficacious, etidronate and zoledronic acid are the most efficacious drugs.
Based on the result discussed above, some efficacious intervention strategies need to be carried out to control the influenza prevalence, such as terminal disinfection, ventilation and reasonable partition.
Furthermore, based on the assumption that to be efficacious, the drug should achieve target inhibition that is at least as great as that associated with efficacy in the rat model (Tanaka et al, 2008), and accepting the modelling assumption of a similar pharmacokinetic pharmacodynamic relationship for tumour in patients and in rats, 20 30 mg was identified as the minimal weekly dose.
Based on the standards of evidence for efficacious interventions laid out by the Society for Prevention Research [ 22], 46 strategies meet scientific criteria for efficacy by having consistent, positive outcomes from at least two high-quality experimental or quasi-experimental trials using a comparison group or interrupted time-series design (Additional file 1).
The recommendation is based on the evidence that IPT is both efficacious [ 3, 4] and relatively inexpensive [ 2, 5].
The probability of being the most efficacious treatment based on the percentage of patients gaining at least 15 letters was 39% for aflibercept, 35% for ranibizumab monotherapy, 24% for ranibizumab plus laser photocoagulation, 2% for dexamethasone, 1% for sham intervention and <1% for laser monotherapy.
These treatments seem to be extremely efficacious and are based on the notion that the microbial populations within the stool of the healthy donor are able to repopulate and colonise the abnormal gut of the patient and thereby affect a cure.
This recommendation is based on the longstanding assumption that the medicine is efficacious, given the lack of historical and contemporary evidence to the contrary.
As the aim of this trial is to use tDCS to boost the effect of exercise, the intervention duration has been selected based on the number of sessions required to achieve efficacious outcomes using exercise alone in knee OA.
