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The cleansing algorithm of Cong et al.'s BatchRepair and IncRepair is, just like their predecessor [14], a cost-based algorithm where the optimal repair is chosen based on the editing cost from the original data [2], measured in Levenstein's edit distance [15], or measured by the number of tuples to be removed [16].
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Traditionally, string similarity is measured in terms of edit distance, which reflects the minimum-cost edit of one string to the other, based on the edit operations of substitutions (including matches) and deletions/insertions (indels).
This method is based on the edit-distance of potential contamination to different target genomes (here, of human and horse).
To the best of our knowledge, TUIUIU is the first filter for multiple repeats based on the edit distance that takes a multiple alignment task into account.
The main approach of approximate string matching has always, until now, been based on the edit-distance [ 3, 4], the oldest kind of algorithm according to Navarro [ 5, 6].
Calculating the distance between RNA structures have been approached by several methods, some of which are based on the edit distance of a tree representation of the RNA secondary structure elements [ 4- 6].
> The putative histone H3 proteins were categorized into four groups based on the edit distance (Levenshtein distance), which is a similarity measure defined for two sequences (words) that requires a minimum number of operations (delete, insert or substitute) to transform one into the other.
Among the selected, nonoverlapping gene models, a subset of high confidence gene models was further analyzed based on the annotation edit distance (AED) score of < 0.20 with canonical start sites and splice sites.
Computed tomography datasets (0.5 mm thickness; Toshiba Aquilion 64, Japan) for each case were used to reconstruct solid models with grey-level processing with the MIMICS 15.1 software based on the "Thresholding", "Edit Masks", and "Calculate 3D" functions.
The model was built using the software MODELLER 19 based on the manually edited alignment of OR83b and bovine rhodopsin 20 (1F88: PDB ID) sequence (Supplementary Fig. S2A) giving rise to Model 1. OR22a sequence and bovine rhodopsin (1F88: PDB ID) sequence were aligned (Fig. S2D) in a method similar to that mentioned for OR83b (Fig. 1) and model of OR22a was built using MODELLER.
We propose a novel, highly tumor-specific delivery system for TP53, based on the CRISPR/Cas9 genome editing technology.
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