Sentence examples for based on the dd from inspiring English sources

A genetic predisposition to diabetic nephropathy based on the DD genotype has been reported in several studies [32] [34], but remains controversial [35].

Thus, both pathways are incomplete in R. litoralis; however, if the two clusters are combined, a degradation mechanism based on the DD-pathway may be functional for both sugars.

The model of the complete CD95 DISC core structure was assembled on the crystal structure of Apo2L/TRAIL in a complex with death receptor 5 (PDB ID 1dog [52]): CD95 ECD and TM domains were modeled as described above and the model of the CD95 DD domain was based on the CD95 DD crystal structure from the CD95/FADD DDs complex (PDB ID 3ezq [16]).

Therefore, we modeled the RIP1 DD structure based on the structure of Fas DD (PDB id 3OQ9) and mapped the mutations that might disrupt the formation of the RIP1 DD/FADD DD complex on the modeled structure of RIP1 DD.

However, in these cases, the results are not robust across all subsample analyses and/or the effect is short-lived and we therefore are unable to reject null hypotheses based on the evidence in the DD analysis.

If the present structure is superimposed on the mDia1 DAD complex (PDB ID 2BAP) based on the alignment of the DD domain, rotations of 43° and translations of approximately 15 Å are required to bring the DID domains into register.

We generated a model for the death domain (DD) of human IRAK-M (IRAK-M-DD) by homology modeling based on the crystal structure of the DD of mouse IRAK-4 (PDB 2A9I [ 21], which has 28.7% sequence identity to the human IRAK-M DD as described in the Methods section).

To model free full-length CD95 receptor as envisaged on a plasma membrane the CD95 ECD and TM domains were modeled as described above and the model of CD95 DD domain was based on the NMR structure of CD95 DD in solution (PDB ID 1ddf, [51]) added.

Projections from a homology model of the RIP1 DD/FADD DD complex based on the structure of the Fas DD/FADD DD complex (see below) are in good agreement with the experimental class averages.

We therefore modeled the structure of the RIP1 DD/FADD DD complex based on the available structure of the Fas DD/FADD DD complex.

Given their apparent similarity in assembly, we modeled the structure of the RIP1 DD/FADD DD complex based on the previously determined structure of the Fas DD/FADD DD complex.