Sentence examples for based on the conformation from inspiring English sources

Based on the conformation of parent ions, the optimization of product ions was performed in the MS2 scan mode.

The design of these cyclic compounds was based on the conformation of the HJ loop within the X-ray structure of GRK2.

The alignment of the molecules was based on the conformation of a structurally related ligand bound to the αIIBβ3 and αvβ3 integrins in X-ray crystallographic studies.

To develop lower weight BACE1 inhibitors, a series of tripeptidic BACE1 inhibitors were devised using a design approach based on the conformation of a virtual inhibitor bound to the BACE1 active site, also called 'in-silico conformational structure-based design'.

The default box size of x = 30.66 Å, y = 27.98 Å and z = 22.50 Å (Fig. 5a) was calculated based on the conformation of NADP bound to its target in the crystal structure, whereas the optimized box size of x = y = z = 18.88 Å (Fig. 5b) was calculated from the R g of NADP.

Based on the conformation of the α-methyl chalcone TUB091 in its complex with tubulin, a series of conformational mimetics have been designed and synthesized where the methyl group of the chalcone has been fused to phenyl ring B resulting in 1,2,3,4-tetrahydronaphthalen-2-yl aryl ketones.

An optimum alignment rule was devised based on the conformations obtained from the molecular mechanics studies, using a common substructure alignment method.

We have presented a new protein protein docking approach to model heterodimeric structures based on the conformations of the monomeric units.

Recently, Jabobs et al classified 426 structures corresponding to 71 distinct human protein kinases, based on the conformations of two structural elements.

A recent clustering of public protein kinase structures based on the conformations of two structural elements, the activation segment (DFG-motif) and the αC-helix, revealed three discrete clusters [40].

Based on the conformations of the catalytic loop, these structures can be classified into two distinct classes: the catalytic inactive) and catalytic active) forms.