Sentence examples for based on the attenuated from inspiring English sources

Based on the attenuated osteoconductive potential of wild-type GDF-5 in the calvaria, we assume that this process as for the induction of ALP expression in ATDC-5 cells involves the type I receptor BMPR-IA.

A similar approach is being developed based on the attenuated DENV-2 virus, DENV-2 PDK-53, and three chimaeric viruses containing the prM and E genes of DENV-1, DENV-3, and DENV-4 virus in the genetic backbone of the DENV-2 PDK-53 virus (termed DENVax).

Current surface plasmon resonance (SPR) modes based on the attenuated total reflection (ATR) method can broadly be categorized as: conventional SPR, long-range SPR (LRSPR), coupled plasmon-waveguide resonance (CPWR), and waveguide-coupled SPR (WCSPR).

The current live vaccine, based on the attenuated strain T1/44, confers limited efficacy although it has been reported to have a degree of pathogenicity [ 1, 2].

One of these vectors is based on the highly attenuated modified vaccinia virus Ankara (MVA) that was originally obtained by attenuation over more than 500 passages in chicken embryo fibroblast cultures [1], [2].

The oncolytic MVs utilized in these studies were based on the highly attenuated Edmonston vaccine strain [ 9].

The immunogenicity profile and the efficacy of a novel CHIKV vaccine candidate based on the highly attenuated poxvirus vector modified vaccinia virus Ankara (MVA) expressing the CHIKV structural genes C, E3, E2, 6K, and E1 (termed MVA-CHIKV) have been generated and characterized [ 101].

Although the only licensed T. gondii vaccine, which is based on the attenuated-live T. gondii S48 strain (Toxovax®), can be used to prevent the incidence of abortion in sheep [ 13], further exploration of its use in other food-producing animals or in humans has been hampered by safety concerns on the possibility of its reversion to a virulence wild type.

Although the only licensed vaccine based on the attenuated-live T. gondii S48 strain (Toxovax®) can be used to prevent the incidence of abortion in sheep [ 11], it is limited to be further explored in food-producing animals or humans in view of the safety concerns on its reverting to a virulence wild type.

The vaccine seed viruses to be generated are based on the live attenuated cold-adapted influenza virus vaccines developed by Maassab and colleagues at the University of Michigan in the 1960s (28 ) and used as the basis for the FluMist vaccine (MedImmune, Inc., Gaithersburg, MD, USA) now licensed in the United States for persons 5 49 years of age for preventing interpandemic influenza.

This chimeric protein contains the V3 region of the gp120 from eight different HIV-1 isolates and was efficiently expressed by a DNA vector (DNA-TAB), and also by vaccinia virus recombinants (rVV) based either on the attenuated modified vaccinia virus Ankara (MVA-TAB) or Western Reserve (VV-TAB) strains.