People must be referred to the laboratory through a doctor to receive these tests, which cost $200 to $300 and are based on technology developed during the sequencing of the human genome.
Based on technological advancements with DNA sequencing technology, along with the significant drop in the cost of sequencing, it is time to consider a comprehensive gene panel for hereditary breast and ovarian cancer genetic testing.
Based on sequencing technology, this type of mRNA abundance assay could avoid the potential cross-hybridization problem occuring between homologous genes in the microrarry experiments.
Recently, RNA sequencing technology, based on next-generation sequencing technology, provides a platform for measuring differences in gene expression [ 32].
The latter catch phrase anyway will have to suffer increasing unpopularity with the prediction that RNA and DNA microarray technologies will soon lose most of their importance, as they will be gradually replaced by methods based on sequencing technologies in the coming years.
SAGE [ 235], CAGE [ 236], and MPSS [ 237], all tag-based sequencing approaches, are based on Sanger sequencing technology.
A new generation of sequencing technologies based on sequencing by synthesis and sequencing by ligation are revolutionizing biology, biotechnology, and medicine [ 1, 2].
The combination of RNA-seq and DGE analysis based on Illumina sequencing technology provided comprehensive information on gene expression.
Proton RNA-seq is based on semiconductor sequencing technology with emulsion PCR amplified libraries bound to Ion spheres.
Using targeted analysis of BRCA1 as an example, we have simulated and mutated a test dataset based on Illumina sequencing technology.
