Sentence examples for based on targets of from inspiring English sources

The k-clique method in the SubpathwayMiner software was used to mine LAPs based on targets of differentially expressed miRNA as well as mRNA expression data [ 28, 29].

Our observations have potential implications for future therapeutic strategies based on targeting of cell cycle deregulation such as via cyclin-dependent kinase (CDK) inhibition.

The proposed technique was based on targeting of α v β3, a key integrin protein of placental angiogenesis.

It could be expected that an efficient therapy based on targeting of HER2 would tend to induce a selection for cells with low or no HER2 expression.

Our approach is based on targeting of a quenched fluorescent pHLIP-FIRE construct to acidic tumors and activation of the fluorescence by translocating the cargo dye into cells, where the reducing power of the cytosol triggers the enhanced fluorescence.

Importantly, these traits molecular mechanisms aside are essential characteristics of all life-threatening cancers, and therapies based on targeting of these characteristics molecularly are therefore broadly applicable to most if not all cancers.

Although we cannot totally rule out that this partially results from virus-host and host-host interactome incompleteness, it is also highly suggestive of viral strategy based on targeting of poorly connected proteins within the human interactome.

Our results were based on target prediction of the 'classic' form of KLK genes.

The remainder of the paper presents the results of these simulations and evaluate different vaccination policies based on targeting some of these group types.

Scaling factor, based on target intensity of 500, Young: 1.34±0.25, Aged: 1.27±0.20; as well as % Present- Young: 67.5±1.0, Aged: 66.6±1.9 were not significantly different across treatment groups (t-test, p>0.3).

Currently, adjuvant endocrine therapies are primarily based on targeting expression of hormone receptors (Goldhirsch et al, 2007).